Invention Grant
- Patent Title: Fc variants having increased affinity for fcyrllc
- Patent Title (中): Fc变体对fcyrllc具有增加的亲和力
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Application No.: US11765353Application Date: 2007-06-19
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Publication No.: US08735545B2Publication Date: 2014-05-27
- Inventor: Gregory Alan Lazar , Wei Dang , John Desjarlais , Sher Bahadur Karki , Omid Vafa , Robert Hayes , Jost Vielmetter
- Applicant: Gregory Alan Lazar , Wei Dang , John Desjarlais , Sher Bahadur Karki , Omid Vafa , Robert Hayes , Jost Vielmetter
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Monrovia
- Agency: Morgan, Lewis & Bockius, LLP
- Agent Robin M. Silva; Ada O. Wong
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; C07K17/00
Abstract:
The present invention relates to Fc variants having increased affinity for FcγRIIc, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.
Public/Granted literature
- US20070248602A1 Fc Variants Having Increased Affinity for FcyRllc Public/Granted day:2007-10-25
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