Invention Grant
- Patent Title: Histone demethylase inhibitors and methods for using the same
- Patent Title (中): 组蛋白脱甲基酶抑制剂及其使用方法
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Application No.: US13691507Application Date: 2012-11-30
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Publication No.: US08735622B2Publication Date: 2014-05-27
- Inventor: Xiang Wang , Wenqing Xu
- Applicant: Xiang Wang , Wenqing Xu
- Applicant Address: US CO Denver
- Assignee: The Regents of the University of Colorado, a body corporate
- Current Assignee: The Regents of the University of Colorado, a body corporate
- Current Assignee Address: US CO Denver
- Agency: Hamilton DeSanctis & Cha, LLP
- Agent Don D. Cha
- Main IPC: C07C271/00
- IPC: C07C271/00
Abstract:
The present invention provides compounds, or derivatives or prodrugs thereof, that comprise a methyllysine mimic, and an α-ketoglutarate mimic that are attached through a linker and methods for using and producing the same. In some embodiments, compounds of the invention are of the formula: M-L-K, or a derivative or a prodrug thereof, wherein M is a methyllysine mimic, L is a linker, and K is an α-ketoglutarate mimic.
Public/Granted literature
- US20130137720A1 HISTONE DEMETHYLASE INHIBITORS AND METHODS FOR USING THE SAME Public/Granted day:2013-05-30
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