Invention Grant
US08741259B2 Low molecular weight thyroid stimulating hormone receptor (TSHR) agonists
有权
低分子量促甲状腺激素受体（TSHR）激动剂
- Patent Title: Low molecular weight thyroid stimulating hormone receptor (TSHR) agonists
- Patent Title (中): 低分子量促甲状腺激素受体（TSHR）激动剂
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Application No.: US13125045Application Date: 2008-10-20
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Publication No.: US08741259B2Publication Date: 2014-06-03
- Inventor: Marvin C. Gershengorn , Susanne Neumann , Bruce M. Raaka , Craig J. Thomas , James Inglese , Noel T. Southall , Steven Titus , Wei Zheng , Wenwei Huang , Gerd Krause , Gunnar Kleinau
- Applicant: Marvin C. Gershengorn , Susanne Neumann , Bruce M. Raaka , Craig J. Thomas , James Inglese , Noel T. Southall , Steven Titus , Wei Zheng , Wenwei Huang , Gerd Krause , Gunnar Kleinau
- Agency: Klarquist Sparkman LLP
- International Application: PCT/US2008/011958 WO 20081020
- International Announcement: WO2010/047674 WO 20100429
- Main IPC: A61K51/00
- IPC: A61K51/00 ; C07D239/88 ; C07D217/24 ; A61K31/47 ; A61P35/00 ; A61K31/167 ; A61K31/517 ; C07C233/01
Abstract:
Disclosed are oxo-hydroquinazolines that are useful as selective TSHR agonists. The compounds may be used for detecting or treating thyroid cancer, or treating a bone degenerative disorder.
Public/Granted literature
- US20110195018A1 LOW MOLECULAR WEIGHT THYROID STIMULATING HORMONE RECEPTOR (TSHR) AGONISTS Public/Granted day:2011-08-11
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