Invention Grant
- Patent Title: Fusion proteins for delivery of GDNF to the CNS
- Patent Title (中): 用于将GDNF递送至CNS的融合蛋白
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Application No.: US12323232Application Date: 2008-11-25
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Publication No.: US08741260B2Publication Date: 2014-06-03
- Inventor: William M. Pardridge , Ruben J. Boado
- Applicant: William M. Pardridge , Ruben J. Boado
- Applicant Address: US CA Santa Monica
- Assignee: Armagen Technologies, Inc.
- Current Assignee: Armagen Technologies, Inc.
- Current Assignee Address: US CA Santa Monica
- Agency: Wilson, Sonsini, Goodrich & Rosati
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K38/18 ; C07K14/48 ; C07K14/485 ; C07K14/49 ; C07K14/495
Abstract:
The invention provides compositions, methods, and kits for increasing transport of GDNF across the blood brain barrier while allowing its activity to remain substantially intact. The GDNF is transported across the blood brain barrier via one or more endogenous receptor-mediated transport systems.
Public/Granted literature
- US20090156498A1 FUSION PROTEINS FOR DELIVERY OF GDNF TO THE CNS Public/Granted day:2009-06-18
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