Invention Grant
- Patent Title: Anti-cMet antibody
- Patent Title (中): 抗cMet抗体
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Application No.: US13132211Application Date: 2009-12-02
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Publication No.: US08741290B2Publication Date: 2014-06-03
- Inventor: Liliane Goetsch , Thierry Wurch , Cédric Bes
- Applicant: Liliane Goetsch , Thierry Wurch , Cédric Bes
- Applicant Address: FR Boulogne-Billancourt
- Assignee: Pierre Fabre Medicament
- Current Assignee: Pierre Fabre Medicament
- Current Assignee Address: FR Boulogne-Billancourt
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
- Priority: WOPCT/IB2008/055663 20081202
- International Application: PCT/EP2009/066201 WO 20091202
- International Announcement: WO2010/069765 WO 20100624
- Main IPC: A61K39/395
- IPC: A61K39/395

Abstract:
Antibodies capable of binding to the human c-Met receptor and/or capable of inhibiting the tyrosine kinase activity of said receptor, with an improved antagonistic activity, the antibodies comprising a modified hinge region. A composition comprising one or more of such antibodies antagonist to c-Met and its use as a medicament for treating cancer.
Public/Granted literature
- US20110239316A1 ANTI-cMET ANTIBODY Public/Granted day:2011-09-29
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