Invention Grant
- Patent Title: Preparation of isolated agonist anti-EDAR monoclonal antibodies
- Patent Title (中): 制备分离的激动剂抗EDAR单克隆抗体
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Application No.: US13791055Application Date: 2013-03-08
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Publication No.: US08741297B2Publication Date: 2014-06-03
- Inventor: Pascal Schneider , Nathalie Dunkel , Stéphane Demotz
- Applicant: Edimer Pharmaceuticals, Inc. , Universite de Lausanne
- Applicant Address: US MA Cambridge CH Lausanne
- Assignee: Edimer Pharmaceuticals, Inc.,Universite de Lausanne
- Current Assignee: Edimer Pharmaceuticals, Inc.,Universite de Lausanne
- Current Assignee Address: US MA Cambridge CH Lausanne
- Agency: DT Ward, PC
- Agent Donna T. Ward; Lingyun Jia
- Priority: WOPCT/IB2009/005118 20090330
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28
Abstract:
The present invention concerns the preparation of substantially purified agonist anti-EDAR monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof. The invention further relates to isolated agonist anti-EDAR monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof as well as their use in the treatment of X-linked hypohidrotic ectodermal dysplasia and tooth agenesis. The invention also relates to a pharmaceutical composition comprising said isolated agonist anti-EDAR monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof and to a method of treating X-linked hypohidrotic ectodermal dysplasia and tooth agenesis. Finally, the present invention concerns a pharmaceutical kit comprising said isolated agonist anti-EDAR monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof.
Public/Granted literature
- US20130273046A1 PREPARATION OF ISOLATED AGONIST ANTI-EDAR MONOCLONAL ANTIBODIES Public/Granted day:2013-10-17
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