Invention Grant
US08741313B2 Polypeptide vaccine and vaccination strategy against mycobacterium
有权
多肽疫苗和针对分枝杆菌的疫苗接种策略
- Patent Title: Polypeptide vaccine and vaccination strategy against mycobacterium
- Patent Title (中): 多肽疫苗和针对分枝杆菌的疫苗接种策略
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Application No.: US12812541Application Date: 2009-01-12
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Publication No.: US08741313B2Publication Date: 2014-06-03
- Inventor: Suraj Sable , Bonnie B. Plikaytis , Thomas M. Shinnick , Rama Rao Amara , Manl Cheruvu
- Applicant: Suraj Sable , Bonnie B. Plikaytis , Thomas M. Shinnick , Rama Rao Amara , Manl Cheruvu
- Applicant Address: US GA Atlanta US DC Washington
- Assignee: Emory University,The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: Emory University,The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US GA Atlanta US DC Washington
- Agency: Gifford, Krass, Sprinkle, Anderson & Citkowski, P.C.
- International Application: PCT/US2009/030754 WO 20090112
- International Announcement: WO2009/089535 WO 20090716
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/02 ; A61K39/04 ; A61K39/116 ; A61K45/00
Abstract:
A vaccine is provided wherein a polypeptide or combination of peptides from M. tuberculosis is administered to a subject to elicit an immune response. The polypeptide vaccine is administered as part of a prime-boost strategy with BCG vaccine to increase the immunoprotection in a subject such that prevention or elimination of disease is achieved. Finally, a pharmaceutical package is provided that encompasses a polypeptide vaccine for M. tuberculosis that when administered to a subject elicits immunoprotection.
Public/Granted literature
- US20110027349A1 POLYPEPTIDE VACCINE AND VACCINATION STRATEGY AGAINST MYCOBACTERIUM Public/Granted day:2011-02-03
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