Invention Grant
US08741347B2 Method for forming cyclodextrin polymer and lipophilic compound emulsions, resulting emulsions, and compositions including said emulsions
失效
形成环糊精聚合物和亲脂性复合乳液,所得乳液和包括所述乳液的组合物的方法
- Patent Title: Method for forming cyclodextrin polymer and lipophilic compound emulsions, resulting emulsions, and compositions including said emulsions
- Patent Title (中): 形成环糊精聚合物和亲脂性复合乳液,所得乳液和包括所述乳液的组合物的方法
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Application No.: US13265550Application Date: 2010-04-23
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Publication No.: US08741347B2Publication Date: 2014-06-03
- Inventor: Anca-Lucia Laza-Knoerr , Ruxandra Gref , Catherine Amiel , Patrick Couvreur
- Applicant: Anca-Lucia Laza-Knoerr , Ruxandra Gref , Catherine Amiel , Patrick Couvreur
- Applicant Address: FR Paris FR Orsay
- Assignee: Centre National de la Recherche Scientifique—CNRS,Universite Paris—SUD 11
- Current Assignee: Centre National de la Recherche Scientifique—CNRS,Universite Paris—SUD 11
- Current Assignee Address: FR Paris FR Orsay
- Agency: Blank Rome LLP
- Priority: FR0901983 20090423; FR0956088 20090907
- International Application: PCT/FR2010/000330 WO 20100423
- International Announcement: WO2010/122246 WO 20101028
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K47/40 ; A61K9/107 ; A61K8/73 ; A61K8/06

Abstract:
The present invention relates to a method for preparing a cyclodextrin polymer and/or a hydrophilic polymer emulsion having cyclodextrins as well as lipophilic compounds, the emulsions having a remarkable stability. In particular, the method includes: (i) adding a lipophilic compound into an aqueous solution of a cyclodextrin unit polymer or hydrophilic polymer having cyclodextrins; (ii) forming an emulsion from the mixture resulting from step (i). The invention also relates to the resulting emulsions, i.e. stabilized emulsions by a non-covalent and non-crystalline inclusion complex consisting of (i) a cyclodextrin unit polymer or a hydrophilic polymer having cyclodextrins and (ii) a lipophilic compound. The invention also relates to the use of said emulsions in the cosmetic, pharmaceutical and/or agri-food fields.
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