Invention Grant
- Patent Title: Gene expression signature of genomic instability in breast cancer
- Patent Title (中): 乳腺癌基因组不稳定基因表达特征
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Application No.: US13119101Application Date: 2009-09-15
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Publication No.: US08741574B2Publication Date: 2014-06-03
- Inventor: Karl Thomas Ried , Jens Habermann , Nancy Lan Guo , Gert Auer
- Applicant: Karl Thomas Ried , Jens Habermann , Nancy Lan Guo , Gert Auer
- Applicant Address: US DC Washington US WV Morgantown
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services,West Virginia University Research Corporation
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services,West Virginia University Research Corporation
- Current Assignee Address: US DC Washington US WV Morgantown
- Agency: Leydig, Voit & Mayer, Ltd.
- International Application: PCT/US2009/056931 WO 20090915
- International Announcement: WO2010/031035 WO 20100318
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
Methods of assessing genomic instability in breast cancer tissue by measuring the expression level of genes CDKN2A, SCYA18, STK15, NXF1, cDNA Dkfzp762M127, p28 KIAA0882, MYB, Human clone 23948, RERG, HNF3A, and ACADSB or a nucleic acid sequence comprising about 90% or greater sequence identity to SEQ ID NO: 21 in breast cancer tissue, an array suitable for use in such methods, and related methods and compositions.
Public/Granted literature
- US20110224089A1 GENE EXPRESSION SIGNATURE OF GENOMIC INSTABILITY IN BREAST CANCER Public/Granted day:2011-09-15
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