Invention Grant
- Patent Title: Differentiation of pluripotent stem cells to definitive endoderm lineage
- Patent Title (中): 将多能干细胞分化为定形内胚层谱系
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Application No.: US11736908Application Date: 2007-04-18
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Publication No.: US08741643B2Publication Date: 2014-06-03
- Inventor: Alireza Rezania , Jean Xu
- Applicant: Alireza Rezania , Jean Xu
- Applicant Address: US CA Milpitas
- Assignee: LifeScan, Inc.
- Current Assignee: LifeScan, Inc.
- Current Assignee Address: US CA Milpitas
- Agent Lois A. Gianneschi
- Main IPC: C12N5/00
- IPC: C12N5/00
Abstract:
The present invention provides methods to promote the differentiation of pluripotent stem cells. In particular, the present invention provides an improved method for the formation of pancreatic endoderm, pancreatic hormone expressing cells and pancreatic hormone secreting cells. The present invention also provides methods to promote the differentiation of pluripotent stem cells without the use of a feeder cell layer.
Public/Granted literature
- US20070254359A1 DIFFERENTIATION OF HUMAN EMBRYONIC STEM CELLS Public/Granted day:2007-11-01
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