Invention Grant
- Patent Title: Reprogramming T cells and hematopoietic cells
- Patent Title (中): 重编程T细胞和造血细胞
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Application No.: US13376361Application Date: 2010-06-04
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Publication No.: US08741648B2Publication Date: 2014-06-03
- Inventor: Deepika Rajesh , Amanda Mack
- Applicant: Deepika Rajesh , Amanda Mack
- Applicant Address: US WI Madison
- Assignee: Cellular Dynamics International, Inc.
- Current Assignee: Cellular Dynamics International, Inc.
- Current Assignee Address: US WI Madison
- Agency: Parker Highlander PLLC
- International Application: PCT/US2010/037376 WO 20100604
- International Announcement: WO2010/141801 WO 20101209
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N15/85 ; C12N15/86 ; C12N5/02
Abstract:
Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from CD34+ hematopoietic cells, such as human CD34+ blood progenitor cells, or T cells. Various iPS cell lines are also provided. In certain embodiments, the invention provides novel induced pluripotent stem cells with a genome comprising genetic rearrangement of T cell receptors.
Public/Granted literature
- US20120135525A1 REPROGRAMMING T CELLS AND HEMATOPOIETIC CELLS Public/Granted day:2012-05-31
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