Invention Grant
- Patent Title: Single recombination system and methods of use
- Patent Title (中): 单一重组系统及其使用方法
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Application No.: US13141595Application Date: 2009-12-16
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Publication No.: US08741653B2Publication Date: 2014-06-03
- Inventor: Sonja Leyrer , Katja Fischer
- Applicant: Sonja Leyrer , Katja Fischer
- Applicant Address: DE Munich
- Assignee: Emergent Product Development GmbH
- Current Assignee: Emergent Product Development GmbH
- Current Assignee Address: DE Munich
- Agency: Thompson Coburn LLP
- Priority: EP08022296 20081222
- International Application: PCT/EP2009/009028 WO 20091216
- International Announcement: WO2010/072365 WO 20100701
- Main IPC: C12N15/863
- IPC: C12N15/863 ; C12N15/64 ; C12N7/02 ; C12N5/10
Abstract:
The present invention is directed to a modified poxvirus vector that allows for the generation of recombinant poxviruses by a single recombination event. A modified poxvirus vector comprising at least one reporter gene located between two flanking sequences for homologous recombination is disclosed. Furthermore, a host cell comprising said vector and a method for the generation of recombinant poxviruses using said vector are provided.
Public/Granted literature
- US20120028336A1 Single Recombination System and Methods of Use Public/Granted day:2012-02-02
Information query
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