Invention Grant
US08741659B2 Composition for measuring the binding affinity between nucleic acid and test substance, and use thereof
有权
用于测量核酸和测试物质之间的结合亲合力的组合物及其用途
- Patent Title: Composition for measuring the binding affinity between nucleic acid and test substance, and use thereof
- Patent Title (中): 用于测量核酸和测试物质之间的结合亲合力的组合物及其用途
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Application No.: US13484505Application Date: 2012-05-31
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Publication No.: US08741659B2Publication Date: 2014-06-03
- Inventor: Kazuhiko Nakatani , Jinhua Zhang , Shiori Umemoto , Shinichi Sasaoka , Takahiro Wazaki
- Applicant: Kazuhiko Nakatani , Jinhua Zhang , Shiori Umemoto , Shinichi Sasaoka , Takahiro Wazaki
- Applicant Address: JP Osaka
- Assignee: Osaka University
- Current Assignee: Osaka University
- Current Assignee Address: JP Osaka
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: JP2007-199970 20070731
- Main IPC: G01N21/76
- IPC: G01N21/76

Abstract:
In one embodiment of the present invention, a composition is disclosed for measuring a binding affinity between a nucleic acid and a test substance, which contains an organic fluorescent substance capable of binding to an RNA and which emits fluorescence having an intensity greater while the organic fluorescent substance is liberated from an RNA than while the organic fluorescent substance is bound to an RNA. This enables a highly accurate and easy measurement of a binding affinity between a test substance and a nucleic acid, and allows various substances to be examined as a test substance.
Public/Granted literature
- US20120238029A1 COMPOSITION FOR MEASURING THE BINDING AFFINITY BETWEEN NUCLEIC ACID AND TEST SUBSTANCE, AND USE THEREOF Public/Granted day:2012-09-20
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