Invention Grant
US08741839B2 Polypeptides targeting vascular endothelial growth factor receptor-2 and αvβ3 integrin
有权
靶向血管内皮生长因子受体2和αv&bgr 3整合素的多肽
- Patent Title: Polypeptides targeting vascular endothelial growth factor receptor-2 and αvβ3 integrin
- Patent Title (中): 靶向血管内皮生长因子受体2和αv&bgr 3整合素的多肽
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Application No.: US13145059Application Date: 2010-01-18
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Publication No.: US08741839B2Publication Date: 2014-06-03
- Inventor: Jennifer R. Cochran , Adam Silverman , Douglas Jones , Niv Papo
- Applicant: Jennifer R. Cochran , Adam Silverman , Douglas Jones , Niv Papo
- Applicant Address: US CA Palo Alto
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Palo Alto
- Agency: Bozicevic, Field & Francis LLP
- Agent Pamela J. Sherwood
- International Application: PCT/US2010/021332 WO 20100118
- International Announcement: WO2010/083495 WO 20100722
- Main IPC: A61K38/18
- IPC: A61K38/18 ; A61K38/16 ; C12P21/04 ; C07H21/04

Abstract:
Polypeptides comprising variant vascular endothelial growth factor sequences are provided. The polypeptides are useful in cancer imaging, cancer diagnosis, monitoring and treatment as well as treatment of diseases characterized by excessive neovascularization.
Public/Granted literature
- US20120020889A1 Polypeptides Targeting Vascular Endothelial Growth Factor Receptor-2 and Alpha V Beta 3 Integrin Public/Granted day:2012-01-26
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