Invention Grant
- Patent Title: Storage-stable, functionally intact fibrinogen
- Patent Title (中): 储存稳定,功能完整的纤维蛋白原
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Application No.: US13000934Application Date: 2009-06-22
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Publication No.: US08741846B2Publication Date: 2014-06-03
- Inventor: Johann Eibl
- Applicant: Johann Eibl
- Applicant Address: AT Vienna
- Assignee: Bio-Products & Bio-Engineering AG
- Current Assignee: Bio-Products & Bio-Engineering AG
- Current Assignee Address: AT Vienna
- Agency: Workman Nydegger
- International Application: PCT/AT2009/000248 WO 20090622
- International Announcement: WO2009/155626 WO 20091230
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61P7/08 ; A61B17/06 ; A61B19/02 ; A61L15/00 ; A61K9/00

Abstract:
Method for the production of a fibrinogen solution from an aqueous solution that contains functionally intact fibrinogen and is contaminated with profibrin and/or fibrin monomers and/or fibrin monomer complexes and/or fibrin split products, characterized in that the contaminations are precipitated using a non-denaturing precipitating agent at a temperature ranging from −4° to +4° and calcium ion activity not exceeding that of a 1,000 μM CaCl2 solution and are separated from the solution by means of filtering or centrifugation process.
Public/Granted literature
- US20110114524A1 STORAGE-STABLE, FUNCTIONALLY INTACT FIBRINOGEN Public/Granted day:2011-05-19
Information query
IPC分类: