Invention Grant
US08741856B2 Avermectins and milbemycins for the treatment, prevention or amelioration of flavivirus infections
失效
阿维菌素和米尔倍霉素用于治疗,预防或改善黄病毒感染
- Patent Title: Avermectins and milbemycins for the treatment, prevention or amelioration of flavivirus infections
- Patent Title (中): 阿维菌素和米尔倍霉素用于治疗,预防或改善黄病毒感染
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Application No.: US13503660Application Date: 2010-10-21
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Publication No.: US08741856B2Publication Date: 2014-06-03
- Inventor: Mario Milani De Mayo De Mari , Eloise Mastrangelo , Martino Bolognesi , Xavier De Lamballerie , Boris Pastorino , Johan Neyts , Suzanne Kaptein
- Applicant: Mario Milani De Mayo De Mari , Eloise Mastrangelo , Martino Bolognesi , Xavier De Lamballerie , Boris Pastorino , Johan Neyts , Suzanne Kaptein
- Applicant Address: IT Roma FR Marseille BE Leuven
- Assignee: Consiglio Nazionale Delle Ricerche,Aix-Marseille Universite',Katholieke Universiteit Leuven-K.U. Leuven R&D
- Current Assignee: Consiglio Nazionale Delle Ricerche,Aix-Marseille Universite',Katholieke Universiteit Leuven-K.U. Leuven R&D
- Current Assignee Address: IT Roma FR Marseille BE Leuven
- Agent Robert E. Alderson, Jr.
- Priority: EP09174368 20091028
- International Application: PCT/EP2010/065880 WO 20101021
- International Announcement: WO2011/051159 WO 20110505
- Main IPC: A61K31/70
- IPC: A61K31/70

Abstract:
Avermectin and milbemycin compounds, particularly the substance ivermectin, for preparing an antiviral medicament for the treatment, prevention or amelioration of a Flavivirus infection, such as those caused by YFV (yellow fever virus), DENV (Dengue virus), JEV (Japanese encephalitis virus), TBEV (tick-borne encephalitis virus) or MODV (Modoc virus) are provided. The antiviral compositions of the present invention are suitable for oral administration to a Flavivirus-infected subject or a subject at risk of a infection, such as a human or other mammal.
Public/Granted literature
- US20120208778A1 AVERMECTINS AND MILBEMYCINS FOR THE TREATMENT, PREVENTION OR AMELIORATION OF FLAVIVIRUS INFECTIONS Public/Granted day:2012-08-16
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