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US08741861B2 Methods of novel therapeutic candidate identification through gene expression analysis in vascular-related diseases 有权
通过血管相关疾病中基因表达分析的新型治疗候选物鉴定方法

  • Patent Title: Methods of novel therapeutic candidate identification through gene expression analysis in vascular-related diseases
  • Patent Title (中): 通过血管相关疾病中基因表达分析的新型治疗候选物鉴定方法
  • Application No.: US12934950
    Application Date: 2009-03-27
  • Publication No.: US08741861B2
    Publication Date: 2014-06-03
  • Inventor: David M. Mann
  • Applicant: David M. Mann
  • Applicant Address: US CA San Diego
  • Assignee: Vascular Biosciences
  • Current Assignee: Vascular Biosciences
  • Current Assignee Address: US CA San Diego
  • Agency: Lewis Kohn & Fitzwilliam LLP
  • Agent David M. Kohn; Kari Moyer-Henry
  • International Application: PCT/US2009/038685 WO 20090327
  • International Announcement: WO2009/121031 WO 20091001
  • Main IPC: C12N15/11
  • IPC: C12N15/11 ;  A61K38/00 ;  G01N1/00
Methods of novel therapeutic candidate identification through gene expression analysis in vascular-related diseases
Abstract:
The present invention discloses multiple treatment regimens for vascular-related diseases and disorders. The present invention provides for methods of treating vascular-related disorders based on gene expression studies from samples collected from individuals having symptoms of vascular-related disorders. Additionally, methods are disclosed involving diagnostic techniques to focus treatment regimens. Finally, methods of treating vascular-related disorder involving targeting microRNAs are also disclosed.
Abstract(Chinese):

本发明公开了血管相关疾病和病症的多种治疗方案。 本发明提供了基于从具有血管相关病症症状的个体收集的样品的基因表达研究来治疗血管相关病症的方法。 此外，公开了涉及聚焦治疗方案的诊断技术的方法。 最后，还公开了治疗涉及靶向微小RNA的血管相关病症的方法。

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