Invention Grant
US08741866B2 Compositions and methods for inhibiting expression of transthyretin
有权
抑制转甲状腺素蛋白表达的组合物和方法
- Patent Title: Compositions and methods for inhibiting expression of transthyretin
- Patent Title (中): 抑制转甲状腺素蛋白表达的组合物和方法
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Application No.: US13410262Application Date: 2012-03-01
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Publication No.: US08741866B2Publication Date: 2014-06-03
- Inventor: Dinah Wen-Yee Sah , Gregory Hinkle , Rene Alvarez , Stuart Milstein , Qingmin Chen
- Applicant: Dinah Wen-Yee Sah , Gregory Hinkle , Rene Alvarez , Stuart Milstein , Qingmin Chen
- Applicant Address: US MA Cambridge
- Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee: Alnylam Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Fenwick & West LLP
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C12N15/85 ; C07H21/02 ; C07H21/04
Abstract:
The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a transthyretin (TTR) gene, and methods of using the dsRNA to inhibit expression of TTR.
Public/Granted literature
- US20120225927A1 COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF TRANSTHYRETIN Public/Granted day:2012-09-06
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