Invention Grant
US08741870B2 Axl receptor tyrosine kinase aptamer inhibitor for use in therapy
失效
Axl受体酪氨酸激酶适体抑制剂用于治疗
- Patent Title: Axl receptor tyrosine kinase aptamer inhibitor for use in therapy
- Patent Title (中): Axl受体酪氨酸激酶适体抑制剂用于治疗
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Application No.: US13876103Application Date: 2011-10-10
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Publication No.: US08741870B2Publication Date: 2014-06-03
- Inventor: Vittorio De Franciscis , Laura Cerchia
- Applicant: Vittorio De Franciscis , Laura Cerchia
- Applicant Address: IT Roma
- Assignee: Consiglio Nazionale delle Ricerche
- Current Assignee: Consiglio Nazionale delle Ricerche
- Current Assignee Address: IT Roma
- Agency: Lucas & Mercanti, LLP
- Priority: ITRM2010A0537 20101012
- International Application: PCT/EP2011/067624 WO 20111010
- International Announcement: WO2012/049108 WO 20120419
- Main IPC: A61K48/00
- IPC: A61K48/00
Abstract:
The present invention concerns a nucleotide aptamer having the sequence: 5′-AUGAUCAAUCGCCUCAAUUCGACAGGAGGCUCAC-3′(SEQ ID NO: 1) for use in the treatment and/or prevention and/or diagnosis of an Axl receptor tyrosine kinase induced disorder and a pharmaceutical composition comprising the same. The invention also relates to a method for the diagnosis of an Axl receptor tyrosine kinase induced disorder in a patient from which a sample is obtained and related diagnostic kit.
Public/Granted literature
- US20130197070A1 AXL RECEPTOR TYROSINE KINASE APTAMER INHIBITOR FOR USE IN THERAPY Public/Granted day:2013-08-01
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