Invention Grant
US08741897B2 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
有权
糖皮质激素模拟物，其制备方法，药物组合物及其用途
- Patent Title: Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
- Patent Title (中): 糖皮质激素模拟物，其制备方法，药物组合物及其用途
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Application No.: US10947420Application Date: 2004-09-22
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Publication No.: US08741897B2Publication Date: 2014-06-03
- Inventor: Younes Bekkali , Rajashekhar Betageri , Michel J. Emmanuel , Abdelhakim Hammach , Christian Hanke Justus Joachim Harcken , Thomas Martin Kirrane, Jr. , Daniel Kuzmich , Thomas Wai-Ho Lee , Pingrong Liu , Usha R. Patel , John Robert Proudfoot , Hossein Razavi , Doris Riether , Hidenori Takahashi , David S. Thomson , Ji Wang , Renee Zindell
- Applicant: Younes Bekkali , Rajashekhar Betageri , Michel J. Emmanuel , Abdelhakim Hammach , Christian Hanke Justus Joachim Harcken , Thomas Martin Kirrane, Jr. , Daniel Kuzmich , Thomas Wai-Ho Lee , Pingrong Liu , Usha R. Patel , John Robert Proudfoot , Hossein Razavi , Doris Riether , Hidenori Takahashi , David S. Thomson , Ji Wang , Renee Zindell
- Applicant Address: US CT Ridgefield
- Assignee: Boehringer Ingelheim Pharmaceuticals Inc.
- Current Assignee: Boehringer Ingelheim Pharmaceuticals Inc.
- Current Assignee Address: US CT Ridgefield
- Agent Michael P. Morris; Timothy X. Witkowski; Usha R. Patel
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61K31/5377 ; A61K31/4355 ; A61K31/5025 ; A61P25/28 ; A61P9/00 ; A61P35/00 ; A61K31/4402 ; A61K31/4409 ; A61K31/4418 ; A61K31/4406 ; A61K31/497 ; A61K31/506 ; A61K31/4184 ; A61K31/404 ; A61K31/416 ; A61K31/47
Abstract:
Compounds of Formula (IA), (IB), (IC), and (ID) wherein R1, R2, R3, R4, R5, and R6 are as respectively defined herein for Formula (IA), (IB), (IC), and (ID), or a tautomer, prodrug, solvate, or salt thereof; pharmaceutical compositions containing such compounds, and methods of modulating the glucocorticoid receptor function and methods of treating disease-states or conditions mediated by the glucocorticoid receptor function or characterized by inflammatory, allergic, or proliferative processes in a patient using these compounds.
Public/Granted literature
- US20050176706A1 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof Public/Granted day:2005-08-11
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