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US08741899B2 (4-chloro-2-fluoro-N-(2-fluorophenyl)-5-[(8aR)-hexahydropyrrolo-[1,2-a]pyrazin-2(1H)-ylcarbonyl]-benzenesulfonamide, and pharmaceutically acceptable salts thereof 有权
(4-氯-2-氟-N-(2-氟苯基)-5 - [(8aR) - 六氢吡咯并[1,2-a]吡嗪-2(1H) - 基羰基] - 苯磺酰胺及其药学上可接受的盐

  • Patent Title: (4-chloro-2-fluoro-N-(2-fluorophenyl)-5-[(8aR)-hexahydropyrrolo-[1,2-a]pyrazin-2(1H)-ylcarbonyl]-benzenesulfonamide, and pharmaceutically acceptable salts thereof
  • Patent Title (中): (4-氯-2-氟-N-(2-氟苯基)-5 - [(8aR) - 六氢吡咯并[1,2-a]吡嗪-2(1H) - 基羰基] - 苯磺酰胺及其药学上可接受的盐
  • Application No.: US13758615
    Application Date: 2013-02-04
  • Publication No.: US08741899B2
    Publication Date: 2014-06-03
  • Inventor: Qingwei ZhangAndrew O. StewartZhiren Xia
  • Applicant: AbbVie Inc.
  • Applicant Address: US IL North Chicago
  • Assignee: AbbVie Inc.
  • Current Assignee: AbbVie Inc.
  • Current Assignee Address: US IL North Chicago
  • Main IPC: A61K31/495
  • IPC: A61K31/495
(4-chloro-2-fluoro-N-(2-fluorophenyl)-5-[(8aR)-hexahydropyrrolo-[1,2-a]pyrazin-2(1H)-ylcarbonyl]-benzenesulfonamide, and pharmaceutically acceptable salts thereof
Abstract:
The present application relates to calcium channel inhibitors comprising compounds of formula (I), formula (II), formula (III), or formula (IV), wherein L1, R1, R2, R3, R4, R5, R6, R7 and Rc are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
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