Invention Grant
- Patent Title: Deazapurines useful as inhibitors of Janus kinases
- Patent Title (中): 脱氮嘌呤可用作Janus激酶抑制剂
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Application No.: US11732845Application Date: 2007-04-05
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Publication No.: US08741912B2Publication Date: 2014-06-03
- Inventor: Mark Ledeboer , David Messersmith , Francois Maltais , Huai Gao , Tiansheng Wang , Jingrong Cao , John Duffy , Gabriel Martinez-Botella , Cornelia Forster , Marion Wannamaker , Francesco Salituro , Albert Pierce , Luc Farmer , Valerie Marone
- Applicant: Mark Ledeboer , David Messersmith , Francois Maltais , Huai Gao , Tiansheng Wang , Jingrong Cao , John Duffy , Gabriel Martinez-Botella , Cornelia Forster , Marion Wannamaker , Francesco Salituro , Albert Pierce , Luc Farmer , Valerie Marone
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agent Booyong S. Lim
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61P35/00 ; A61P29/00 ; A61P37/06 ; A61P25/16 ; A61P25/28
Abstract:
The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The compounds are generally represented by structural formula I or pharmaceutically acceptable salts thereof:
Public/Granted literature
- US20090088445A1 Deazapurines useful as inhibitors of Janus kinases Public/Granted day:2009-04-02
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