Invention Grant
US08741916B2 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the ORL-1 receptor
有权
1,3,8-三取代1,3,8-三氮杂 - 螺[4.5]癸-4-酮衍生物作为ORL-1受体的配体
![1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the ORL-1 receptor](/docs/US/2014-06-03/US08741916B2/abs.jpg.600x600.jpg)
- Patent Title: 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the ORL-1 receptor
- Patent Title (中): 1,3,8-三取代1,3,8-三氮杂 - 螺[4.5]癸-4-酮衍生物作为ORL-1受体的配体
-
Application No.: US12030911Application Date: 2008-02-14
-
Publication No.: US08741916B2Publication Date: 2014-06-03
- Inventor: Gilles C. Bignan , Dennis J. Hlasta , Richard R. Ryan
- Applicant: Gilles C. Bignan , Dennis J. Hlasta , Richard R. Ryan
- Applicant Address: BE
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE
- Agent Michele G. Mangini
- Main IPC: A61K31/438
- IPC: A61K31/438 ; C07D401/14 ; C07D401/04
![1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the ORL-1 receptor](/abs-image/US/2014/06/03/US08741916B2/abs.jpg.150x150.jpg)
Abstract:
The present invention is directed to novel 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions mediated by the ORL-1 G-protein coupled receptor.
Public/Granted literature
- US20080249122A1 1,3,8-TRISUBSTITUTED-1,3,8-TRIAZA-SPIRO[4.5]DECAN-4-ONE DERIVATIVES AS LIGANDS OF THE ORL-1 RECEPTOR Public/Granted day:2008-10-09
Information query
