Invention Grant
- Patent Title: Modulators of ATP-binding cassette transporters
- Patent Title (中): ATP结合盒转运蛋白的调节剂
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Application No.: US14063785Application Date: 2013-10-25
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Publication No.: US08741925B2Publication Date: 2014-06-03
- Inventor: Sara Hadida-Ruah , Anna Hazlewood , Peter Grootenhuis , Fredrick Van Goor , Ashvani Singh , Jinglan Zhou , Jason McCartney
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Honigman Miller Schwartz and Cohn LLP
- Agent Christopher C. Forbes; Jonathan P. O'Brien
- Main IPC: A61K31/04
- IPC: A61K31/04 ; A61K8/49

Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Public/Granted literature
- US20140051724A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS Public/Granted day:2014-02-20
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