Invention Grant
- Patent Title: Anti-infective agents against intracellular pathogens
- Patent Title (中): 针对细胞内病原体的抗感染剂
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Application No.: US13869386Application Date: 2013-04-24
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Publication No.: US08741944B2Publication Date: 2014-06-03
- Inventor: Ching-Shih Chen , Hao-Chieh Chiu , Dasheng Wang
- Applicant: The Ohio State University Research Foundation
- Applicant Address: US OH Columbus
- Assignee: The Ohio State University Research Foundation
- Current Assignee: The Ohio State University Research Foundation
- Current Assignee Address: US OH Columbus
- Agency: Tarolli, Sundheim, Covell & Tummino LLP
- Main IPC: C07D231/12
- IPC: C07D231/12 ; C07D403/10 ; A61K31/5415
Abstract:
A new class of phosphoinositide-dependent kinase-1 (PDK-1) inhibitors of Formula I: wherein X wherein X is —CF3, Ar is selected from and R is selected from where R′ is L-Lys, D-Lys, β-Ala, L-Lue, L-Ile, Phe, SO2CH2CH2NH2, SO2NH2, Asn, Glu or Gyl, and R″ is methyl, ethyl, allyl, CH2CH2OH, CH2CN, CH2CH2CN, CH2CONH2,
Public/Granted literature
- US20130237575A1 ANTI-INFECTIVE AGENTS AGAINST INTRACELLULAR PATHOGENS Public/Granted day:2013-09-12
Information query
