Invention Grant
US08742101B2 Purine nucleoside analogues for treating flaviviridae including hepatitis C
有权
嘌呤核苷类似物用于治疗黄病毒科，包括丙型肝炎
- Patent Title: Purine nucleoside analogues for treating flaviviridae including hepatitis C
- Patent Title (中): 嘌呤核苷类似物用于治疗黄病毒科，包括丙型肝炎
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Application No.: US12270795Application Date: 2008-11-13
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Publication No.: US08742101B2Publication Date: 2014-06-03
- Inventor: Richard Storer , Gilles Gosselin , David Dukhan , Frederic Leroy
- Applicant: Richard Storer , Gilles Gosselin , David Dukhan , Frederic Leroy
- Applicant Address: US MA Cambridge FR Paris FR Montpellier
- Assignee: Idenix Pharmaceuticals, Inc.,Centre National de la Recherche Scientifique,L'Universite Montpellier II
- Current Assignee: Idenix Pharmaceuticals, Inc.,Centre National de la Recherche Scientifique,L'Universite Montpellier II
- Current Assignee Address: US MA Cambridge FR Paris FR Montpellier
- Agency: Jones Day
- Main IPC: C07H19/12
- IPC: C07H19/12 ; C07H19/056 ; C07H19/04 ; C07D487/04 ; A61K31/53 ; A61K31/341 ; A61P31/14
Abstract:
This invention is directed to a method for treating a host, especially a human, infected with hepatitis C, flavivirus and/or pestivirus, comprising administering to that host an effective amount of an anti-HCV biologically active pentofuranonucleoside where the pentofuranonucleoside base is an optionally substituted 2-azapurine. The optionally substituted pentofuranonucleoside, or a salt or prodrug thereof, may be administered alone or in combination with one or more optionally substituted pentofuranonucleosides or other anti-viral agents.
Public/Granted literature
- US20090169507A1 PURINE NUCLEOSIDE ANALOGUES FOR TREATING FLAVIVIRIDAE INCLUDING HEPATITIS C Public/Granted day:2009-07-02
Information query
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