Invention Grant
US08742124B2 Amide derivatives bearing a cyclopropylaminoacarbonyl substituent useful as cytokine inhibitors
有权
含有环丙基氨基羰基取代基的酰胺衍生物可用作细胞因子抑制剂
- Patent Title: Amide derivatives bearing a cyclopropylaminoacarbonyl substituent useful as cytokine inhibitors
- Patent Title (中): 含有环丙基氨基羰基取代基的酰胺衍生物可用作细胞因子抑制剂
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Application No.: US13628958Application Date: 2012-09-27
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Publication No.: US08742124B2Publication Date: 2014-06-03
- Inventor: Dearg Sutherland Brown , John Graham Cumming , Ian Alun Nash
- Applicant: AstraZeneca AB
- Applicant Address: SE Sodertalje
- Assignee: AstraZeneca AB
- Current Assignee: AstraZeneca AB
- Current Assignee Address: SE Sodertalje
- Agency: Dechert LLP
- Priority: GB0329572.2 20031220
- Main IPC: C07D213/56
- IPC: C07D213/56
Abstract:
The invention concerns a compound of the Formula (I), wherein Qa is heteroaryl and is substituted with halogeno; R1 and R2 are hydrogen; and Qb is phenyl or heteroaryl, and Qb may optionally bear 1 or 2 substituents selected from hydroxy, halogeno and (1-6C)alkyl, or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.
Public/Granted literature
- US20130035346A1 AMIDE DERIVATIVES BEARING A CYCLOPROPYLAMINOACARBONYL SUBSTITUENT USEFUL AS CYTOKINE INHIBITORS Public/Granted day:2013-02-07
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