Invention Grant
US08742205B2 Dominant negative mutant KRP protein protection of active cyclin-CDK complex inhibition by wild-type KRP
有权
主要负性突变体KRP蛋白保护活性细胞周期蛋白 - CDK复合物抑制野生型KRP
- Patent Title: Dominant negative mutant KRP protein protection of active cyclin-CDK complex inhibition by wild-type KRP
- Patent Title (中): 主要负性突变体KRP蛋白保护活性细胞周期蛋白 - CDK复合物抑制野生型KRP
-
Application No.: US11460941Application Date: 2006-07-28
-
Publication No.: US08742205B2Publication Date: 2014-06-03
- Inventor: Paul Olivier , Jay DeRocher , James M. Roberts
- Applicant: Paul Olivier , Jay DeRocher , James M. Roberts
- Applicant Address: US WA Seattle
- Assignee: Targeted Growth, Inc.
- Current Assignee: Targeted Growth, Inc.
- Current Assignee Address: US WA Seattle
- Agency: Cooley LLP
- Main IPC: A01H1/00
- IPC: A01H1/00 ; A01H5/00 ; C12N15/87 ; C12N15/82 ; C12N5/04 ; C12N5/10 ; C07H21/04
Abstract:
Disclosed are mutant CDK inhibitor (CKI) polypeptides having dominant negative antagonist activity against wild-type CKI proteins, as well as related compositions, including nucleic acids and vectors encoding the mutant CKI polypeptides and transformed host cells and transgenic plants comprising such nucleic acids and vectors. Also disclosed are related methods for using the mutant proteins to modulate cell division in cells, particularly plant cells.
Public/Granted literature
- US20070056058A1 DOMINANT NEGATIVE MUTANT KRP PROTEIN PROTECTION OF ACTIVE CYCLIN-CDK COMPLEX INHIBITION BY WILD-TYPE KRP Public/Granted day:2007-03-08
Information query
