A control device of a machine tool includes a first determination unit determining an amount of rotation, rotational speed, and direction of rotation of a rotary handle based on a pulse signal generated by rotation of the rotary handle at a manual pulse generator, and a second determination unit determining which of position control and rotational speed control is selected by selection of an axis through an axis selector switch, based on a signal generated by an axis selection signal generator at an operation device including the manual pulse generator. When a determination is made that position control is selected, the control device controls the amount and direction of travel of a spindle based on the amount of rotation and direction of rotation of the rotary handle. When a determination is made that rotational speed control is selected, the control device controls the rotational speed and direction of rotation of a table based on the rotational speed and direction of rotation of the rotary handle. Accordingly, the user can readily set the direction of rotation and rotational speed of the table using the manual pulse generator, and cause the table to move at the set direction of rotation and rotational speed.