The disclosed invention relates to a transceiver system configured to cancel RF second-order intermodulation distortion (IMD2) within a differential reception path. In some embodiments, the transceiver system has one or more common-mode attenuation elements that attenuate common-mode interferer signals within the differential reception path. The common-mode attenuation elements detect a common-mode interferer from one or more nodes within a transceiver system front-end. One or more properties of the detected common-mode interferer are adjusted and then fed into the differential reception path, where the adjusted common-mode signal attenuates the common-mode interferers. In other embodiments, the differential reception path has a tunable amplifying stage. The tunable amplifying stage has first and second amplifier elements that are independently operated to intentionally introduce an operating parameter mismatch between the elements. The intentional mismatch may be tuned to account for different nonlinear responses of the amplifier elements to mitigate IMD2 within the differential reception path.