A device and a method for managing a piezo inkjet head. The device includes: a piezo actuator connected to an inkjet head to generate pressure; a driver that controls driving of the piezo actuator; a sensing resistor connected between the driver and the piezo actuator, a signal amplifier connected across the sensing resistor to amplify the signal applied to the sensing resistor; a signal processor that removes noise of the signal output from the signal amplifier; a controller that determines a signal passing through the signal processor as a reference signal in a state in which bubbles are not introduced into the inkjet head; and a storage unit that stores the signal determined as the reference signal in the controller. The controller calculates a difference between the signal passing through the signal processor and the reference signal to generate a detection signal and determine a state of the inkjet head.