An endovascular prosthetic system comprising an prosthetic device with a major lumen extending therethrough, a major wall, at least one opening in the major wall; at least one branch extending into the major lumen of the prosthetic device having a minor lumen, a minor wall, and a fenestration in the minor wall in communication with the major lumen; and at least one guide wire extending through the fenestration and out of the prosthesis through the opening.