Invention Grant
- Patent Title: Tracking of bone marrow cells for metastasis screening
- Patent Title (中): 跟踪骨髓细胞进行转移筛选
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Application No.: US12974214Application Date: 2010-12-21
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Publication No.: US08747839B2Publication Date: 2014-06-10
- Inventor: Christian Geppert , Arne Hengerer , Sven Meyburg , Sebastian Schmidt , Susanne Schmolke , Ralph Markus Wirtz
- Applicant: Christian Geppert , Arne Hengerer , Sven Meyburg , Sebastian Schmidt , Susanne Schmolke , Ralph Markus Wirtz
- Applicant Address: DE Munich DE Marburg
- Assignee: Siemens Aktiengesellschaft,Siemens Healthcare Diagnostics Products GmbH
- Current Assignee: Siemens Aktiengesellschaft,Siemens Healthcare Diagnostics Products GmbH
- Current Assignee Address: DE Munich DE Marburg
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: DE102009060317 20091223
- Main IPC: A01N63/02
- IPC: A01N63/02 ; A61K35/32 ; A61K51/02 ; A61B5/055

Abstract:
At least one embodiment of the invention relates to bone marrow precursor cells or bone marrow cells of a patient, the cells labeled with at least one contrast agent suitable for an imaging method, for use in an imaging method for diagnosing a metastasizing cancer, wherein the local accumulation of the labeled precursor cells or bone marrow cells indicates the presence of a metastasizing tumor growth. At least one embodiment also relates to a method for imaging a metastasizing tumor tissue in a patient, wherein a) bone marrow precursor cells or bone marrow cells are extracted from a patient, b) these precursor cells or bone marrow cells are labeled with at least one contrast agent suitable for an imaging method, c) the precursor cells or bone marrow cells thus labeled are retransplanted or reinjected into the patient, and d) the presence of metastasizing tumor cells is depicted with an imaging method. At least one embodiment also relates a method for imaging a metastasizing tumor tissue, wherein a suitable imaging method is used to image bone marrow precursor cells and/or bone marrow cells that are accumulated in a metastasizing tumor tissue and labeled with at least one contrast agent suitable for an imaging method.
Public/Granted literature
- US20110150758A1 TRACKING OF BONE MARROW CELLS FOR METASTASIS SCREENING Public/Granted day:2011-06-23
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