Invention Grant
US08747860B2 Methods and compositions to modulate antiviral and immune activity responses
有权
调节抗病毒和免疫活性反应的方法和组合物
- Patent Title: Methods and compositions to modulate antiviral and immune activity responses
- Patent Title (中): 调节抗病毒和免疫活性反应的方法和组合物
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Application No.: US13542581Application Date: 2012-07-05
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Publication No.: US08747860B2Publication Date: 2014-06-10
- Inventor: Carrie M. Rosenberger , Alan A. Aderem
- Applicant: Carrie M. Rosenberger , Alan A. Aderem
- Applicant Address: US WA Seattle
- Assignee: Institute for Systems Biology
- Current Assignee: Institute for Systems Biology
- Current Assignee Address: US WA Seattle
- Agency: Morrison & Foerster LLP
- Main IPC: A61K39/12
- IPC: A61K39/12 ; C12N7/00 ; C12N7/02 ; C12N7/04
Abstract:
The invention is directed to an improved method to manufacture virus for use in vaccine by culturing infected cells that have been modified to overexpress miR-144. The invention is also directed to manipulating the activity or level of miR-144 in subjects in order to modulate the antiviral and immune response systems.
Public/Granted literature
- US20130022602A1 METHODS AND COMPOSITIONS TO MODULATE ANTIVIRAL AND IMMUNE ACTIVITY RESPONSES Public/Granted day:2013-01-24
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