Invention Grant
- Patent Title: Ceramide anionic liposome compositions
- Patent Title (中): 神经酰胺阴离子脂质体组合物
-
Application No.: US13468578Application Date: 2012-05-10
-
Publication No.: US08747891B2Publication Date: 2014-06-10
- Inventor: Mark Kester , Sriram S. Shanmugavelandy , Todd Fox
- Applicant: Mark Kester , Sriram S. Shanmugavelandy , Todd Fox
- Applicant Address: US PA University Park
- Assignee: The Penn State Research Foundation
- Current Assignee: The Penn State Research Foundation
- Current Assignee Address: US PA University Park
- Agency: McKee, Voorhees & Sease, P.L.C.
- Main IPC: A61K31/475
- IPC: A61K31/475 ; A61K9/127 ; A61K31/44 ; A61K31/7076 ; A61P35/00 ; B01J13/04
Abstract:
Described herein are pharmaceutical compositions according to aspects of the present invention which include one or more hydrophilic antineoplastic chemotherapeutics, such as vinca alkyloid antineoplastic chemotherapeutics, encapsulated in ceramide anionic liposomes. Methods of treatment of a subject having cancer using the pharmaceutical compositions are described, along with methods of making ceramide anionic liposomes which encapsulate one or more hydrophilic antineoplastic chemotherapeutics in the aqueous interior of the ceramide anionic liposomes.
Public/Granted literature
- US20120288556A1 CERAMIDE ANIONIC LIPOSOME COMPOSITIONS Public/Granted day:2012-11-15
Information query
IPC分类:
