Invention Grant
US08748095B2 Probe for detecting polymorphism in EGFR gene and use of the probe
有权
探测EGFR基因多态性和探针的使用
- Patent Title: Probe for detecting polymorphism in EGFR gene and use of the probe
- Patent Title (中): 探测EGFR基因多态性和探针的使用
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Application No.: US13504177Application Date: 2010-10-29
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Publication No.: US08748095B2Publication Date: 2014-06-10
- Inventor: Moeko Ijuin
- Applicant: Moeko Ijuin
- Applicant Address: JP Kyoto
- Assignee: ARKRAY, Inc.
- Current Assignee: ARKRAY, Inc.
- Current Assignee Address: JP Kyoto
- Agency: Morgan, Lewis & Bockius LLP
- Priority: JP2009-251184 20091030
- International Application: PCT/JP2010/069378 WO 20101029
- International Announcement: WO2011/052754 WO 20110505
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/02 ; C07H21/04
Abstract:
The present invention provides a polymorphism detection probe that can identify a polymorphism in an EGFR gene easily and with high reliability and a polymorphism detection method using the probe. The probe of the present invention is a probe for detecting a polymorphism in an EGFR gene, including at least one of an oligonucleotide (P1) and an oligonucleotide (P2), wherein: (P1) is a 22- to 50-mer oligonucleotide composed of a base sequence complementary to a base sequence including 334th to 355th bases in SEQ ID NO: 1 and having a base complementary to the 334th base in its 3′ end region; and (P2) is an oligonucleotide composed of a base sequence complementary to the oligonucleotide (P1).
Public/Granted literature
- US20120214166A1 Probe for Detecting Polymorphism in EGFR Gene and Use of the Probe Public/Granted day:2012-08-23
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