Invention Grant
- Patent Title: Methods of determining cancer cell responsiveness to a notch inhibitory agent
- Patent Title (中): 确定癌细胞对缺口抑制剂的反应性的方法
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Application No.: US13399556Application Date: 2012-02-17
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Publication No.: US08748112B2Publication Date: 2014-06-10
- Inventor: Spyros Stylianou
- Applicant: Spyros Stylianou
- Applicant Address: GB London
- Assignee: Trojan Technologies, Ltd.
- Current Assignee: Trojan Technologies, Ltd.
- Current Assignee Address: GB London
- Agency: DLA Piper LLP (US)
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/566 ; G01N33/00 ; C07K14/435

Abstract:
The present invention is based on the discovery that the Notch signaling pathway is associated with cancer. Accordingly, the invention provides methods and compositions for treating cancer. Also provided are methods of modulating the expression and/or activity of proteins in the Notch signaling pathway for use in diagnoses and treatment of cancer in a subject.
Public/Granted literature
- US20130022966A1 Methods of Treating Cancer Using Notch Pathway Inhibitors Public/Granted day:2013-01-24
Information query
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