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US08748112B2 Methods of determining cancer cell responsiveness to a notch inhibitory agent 有权
确定癌细胞对缺口抑制剂的反应性的方法

Methods of determining cancer cell responsiveness to a notch inhibitory agent
Abstract:
The present invention is based on the discovery that the Notch signaling pathway is associated with cancer. Accordingly, the invention provides methods and compositions for treating cancer. Also provided are methods of modulating the expression and/or activity of proteins in the Notch signaling pathway for use in diagnoses and treatment of cancer in a subject.
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