Invention Grant
- Patent Title: Generation of choroid plexus epithelial cells from human embryonic stem cells
- Patent Title (中): 从人胚胎干细胞产生脉络丛神经上皮细胞
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Application No.: US13370054Application Date: 2012-02-09
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Publication No.: US08748176B2Publication Date: 2014-06-10
- Inventor: Edwin S. Monuki , Momoko Watanabe
- Applicant: Edwin S. Monuki , Momoko Watanabe
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Berliner & Associates
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N5/07 ; C12N5/00 ; C12N5/02
Abstract:
Choroid plexus epithelial cells are generated in a culture medium using embryonic stem cells and adding an effective amount of bone morphogenetic protein and/or other members of the transforming growth factor beta (TGF-beta) superfamily. Generation of such choroid plexus epithelial cells are confirmed using a combination of genetic markers, antibodies, histology inspection, functional assays, and integration into the endogenous choroid plexus in mice.
Public/Granted literature
- US20120201789A1 GENERATION OF CHOROID PLEXUS EPITHELIAL CELLS FROM HUMAN EMBRYONIC STEM CELLS Public/Granted day:2012-08-09
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