Invention Grant
- Patent Title: Methods for use in human-adapting monoclonal antibodies
- Patent Title (中): 用于人类适应性单克隆抗体的方法
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Application No.: US11875416Application Date: 2007-10-19
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Publication No.: US08748356B2Publication Date: 2014-06-10
- Inventor: Gopalan Raghunathan
- Applicant: Gopalan Raghunathan
- Applicant Address: US PA Horsham
- Assignee: Janssen Biotech, Inc.
- Current Assignee: Janssen Biotech, Inc.
- Current Assignee Address: US PA Horsham
- Agent Kirk Baumeister
- Main IPC: C40B50/06
- IPC: C40B50/06 ; C40B40/10 ; C12P21/08 ; A61K39/395
Abstract:
Methods useful for human adapting non-human monoclonal antibodies are disclosed. The methods select candidate human antibody framework sequences from a database of human germline genes or human sequences with somatic mutations.
Public/Granted literature
- US20090118127A1 Methods for Use in Human-Adapting Monoclonal Antibodies Public/Granted day:2009-05-07
Information query
