Invention Grant
- Patent Title: Pharmaceutical compositions containing quinazoline derivatives for treating as serotonin receptor antagonist
- Patent Title (中): 含有喹唑啉衍生物作为血清素受体拮抗剂治疗的药物组合物
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Application No.: US12195951Application Date: 2008-08-21
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Publication No.: US08748422B2Publication Date: 2014-06-10
- Inventor: Ghil Soo Nam , Hye Whon Rhim , Ae Nim Pae , Hyun Ah Choo , Kyung Il Choi , Seung Yeol Nah
- Applicant: Ghil Soo Nam , Hye Whon Rhim , Ae Nim Pae , Hyun Ah Choo , Kyung Il Choi , Seung Yeol Nah
- Applicant Address: KR Seoul
- Assignee: Korea Institute of Science and Technology
- Current Assignee: Korea Institute of Science and Technology
- Current Assignee Address: KR Seoul
- Agent William E. Beaumont
- Priority: KR10-2007-0084322 20070822
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/517 ; A61P25/00
Abstract:
The present invention relates to a pharmaceutical composition containing one or more quinazoline compounds as an active ingredient, which has antagonistic activity against serotonin 5-HT3A and is effective for the prevention and treatment of central nervous system (CNS) diseases, including emesis, nausea, alcoholism, drug abuse, depression, compulsive neurosis, anxiety, seizure, Alzheimer's disease, Parkinson's disease, Huntington's chorea, psychosis, schizophrenia, suicidal tendency, sleep disorder, appetite disorder and migraine.
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