Invention Grant
- Patent Title: CGRP receptor antagonists
- Patent Title (中): CGRP受体拮抗剂
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Application No.: US13439096Application Date: 2012-04-04
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Publication No.: US08748429B2Publication Date: 2014-06-10
- Inventor: Guanglin Luo , Gene M. Dubowchik , John E. Macor , Ling Chen
- Applicant: Guanglin Luo , Gene M. Dubowchik , John E. Macor , Ling Chen
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent James Epperson
- Main IPC: A61K31/495
- IPC: A61K31/495 ; A01N43/50 ; A01N43/54 ; A01N43/56 ; A01N43/58

Abstract:
The disclosure generally relates to the novel compounds of formula I, including pharmaceutically acceptable salts, which are CGRP receptor antagonists. The disclosure also relates to pharmaceutical compositions and methods for using the compounds in the treatment of CGRP related disorders including migraine and other headaches, neurogenic vasodilation, neurogenic inflammation, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases such as asthma, and chronic obstructive pulmonary disease (COPD).
Public/Granted literature
- US20130096130A1 CGRP Receptor Antagonists Public/Granted day:2013-04-18
Information query