Invention Grant
- Patent Title: Therapeutic peptides
- Patent Title (中): 治疗肽
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Application No.: US13984523Application Date: 2011-06-08
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Publication No.: US08748575B2Publication Date: 2014-06-10
- Inventor: Henry Wolfe , Reinhard Ebner
- Applicant: Henry Wolfe , Reinhard Ebner
- Applicant Address: US MD Chevy Chase
- Assignee: Combimab, Inc.
- Current Assignee: Combimab, Inc.
- Current Assignee Address: US MD Chevy Chase
- Agency: InHouse Patent Counsel, LLC
- Agent Michele M. Wales
- International Application: PCT/US2011/039572 WO 20110608
- International Announcement: WO2011/156453 WO 20111215
- Main IPC: A61K38/04
- IPC: A61K38/04 ; C07K7/08 ; C07K7/00 ; C07K1/107 ; C07K1/00 ; A61K38/10 ; A61K38/00 ; A61P1/10
Abstract:
Therapeutic peptides having guanylyl cyclase C agonist activity are disclosed. The therapeutic peptides are analogues of the E. coli STa peptide with non-natural amino acid, isosteric or D-amino acid substituents. The therapeutic peptides are useful in the treatment of chronic ideopathic constipation, inflammatory bowel disease, and other diseases. Pharmaceutical compositions comprising the therapeutic peptides are also disclosed.
Public/Granted literature
- US20140038881A1 Therapeutic Peptides Public/Granted day:2014-02-06
Information query
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