Invention Grant
- Patent Title: Affinity ligands and methods for protein purification
- Patent Title (中): 亲和配体和蛋白质纯化方法
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Application No.: US13502103Application Date: 2010-10-15
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Publication No.: US08748582B2Publication Date: 2014-06-10
- Inventor: Milton T W Hearn , Anjali Makarand Bhagwat , William Roy Jackson , Simon John Mountford
- Applicant: Milton T W Hearn , Anjali Makarand Bhagwat , William Roy Jackson , Simon John Mountford
- Applicant Address: AU Victoria
- Assignee: Monash University
- Current Assignee: Monash University
- Current Assignee Address: AU Victoria
- Priority: AU2009905049 20091015
- International Application: PCT/AU2010/001368 WO 20101015
- International Announcement: WO2011/044637 WO 20110421
- Main IPC: C07K1/22
- IPC: C07K1/22 ; C07D213/70 ; C07D213/76 ; C07D215/36 ; C07D217/22 ; C07D401/12 ; C07D401/14 ; C08B37/00
Abstract:
The present invention relates generally to affinity ligands and chemical affinity ligand-matrix conjugates for use as chromatographic adsorbents and methods which utilize the adsorbents in the purification of proteins by affinity chromatography. The affinity ligand-matrix conjugates of the present invention comprise ligands of general formula (I): wherein m represents an integer from 0-2, n represents an integer from 0-6, p represents an integer from 0-4, R1 represents H or C1-3 alkyl, R2 is an optional substituent, and X is the position at which the ligand is immobilized, optionally via a linker.
Public/Granted literature
- US20120259094A1 AFFINITY LIGANDS AND METHODS FOR PROTEIN PURIFICATION Public/Granted day:2012-10-11
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