Invention Grant
- Patent Title: Antibodies that bind to OX40 and their uses
- Patent Title (中): 结合OX40的抗体及其用途
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Application No.: US13545708Application Date: 2012-07-10
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Publication No.: US08748585B2Publication Date: 2014-06-10
- Inventor: Antoine Attinger , Stanislas Blein , Jonathan Albert Back , Rami Lissilaa , Samuel Hou
- Applicant: Antoine Attinger , Stanislas Blein , Jonathan Albert Back , Rami Lissilaa , Samuel Hou
- Applicant Address: CH La Chaux-de-Fonds
- Assignee: Glenmark Pharmaceuticals S.A.
- Current Assignee: Glenmark Pharmaceuticals S.A.
- Current Assignee Address: CH La Chaux-de-Fonds
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Agent Timothy J. Shea, Jr.; Erin Heenan
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C07K16/28 ; A61K39/395
Abstract:
The present invention relates to antagonist antibodies or fragments thereof that bind to human OX40. More specifically, the present invention relates to an antagonist antibody or fragment thereof that binds to human OX40 comprising a heavy chain CDR1 comprising the amino acid sequence of SEQ ID NO: 1, and/or a heavy chain CDR2 comprising the amino acid sequence of SEQ ID NO: 2, and/or a heavy chain CDR3 comprising the amino acid sequence of SEQ ID NO: 3; and/or comprising a light chain CDR1 comprising the amino acid sequence of SEQ ID NO: 4, and/or a light chain CDR2 comprising the amino acid sequence of SEQ ID NO: 5 and/or a light chain CDR3 comprising the amino acid sequence of SEQ ID NO: 6.
Public/Granted literature
- US20130183315A1 Antibodies that bind to OX40 and their uses Public/Granted day:2013-07-18
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