Invention Grant
US08748590B2 Oligonucleotides for detection test of polymorphism of EGFR exon 19 and use therof
有权
寡核苷酸用于EGFR外显子19的多态性检测试验，并使用该方法
- Patent Title: Oligonucleotides for detection test of polymorphism of EGFR exon 19 and use therof
- Patent Title (中): 寡核苷酸用于EGFR外显子19的多态性检测试验，并使用该方法
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Application No.: US13461406Application Date: 2012-05-01
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Publication No.: US08748590B2Publication Date: 2014-06-10
- Inventor: Aki Iguchi
- Applicant: Aki Iguchi
- Applicant Address: JP Kyoto
- Assignee: ARKRAY, Inc.
- Current Assignee: ARKRAY, Inc.
- Current Assignee Address: JP Kyoto
- Agency: Morgan, Lewis & Bockius LLP
- Priority: JP2011-103818 20110506; JP2012-094081 20120417
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12Q1/68 ; C12P19/34
Abstract:
An oligonucleotide for a detection test of a polymorphism of EGFR exon 19, the oligonucleotide being at least one selected from the group consisting of a P1 oligonucleotide and a P1′ oligonucleotide, the P1 oligonucleotide having a 3′ end subjected to an extension inhibition treatment, which has an identity of at least 80% with respect to a base sequence including at least the 115th to the 123rd bases of the base sequence indicated in SEQ ID NO: 1 and has a length of from 9 to 80 bases; and the P1′ oligonucleotide having a 3′ end subjected to an extension inhibition treatment, which hybridizes under stringent conditions with a complementary strand of a base sequence including at least the 115th to the 123rd bases of the base sequence indicated in SEQ ID NO: 1 and having a length of from 9 to 80 bases.
Public/Granted literature
- US20120282610A1 Oligonucleotides for Detection Test of Polymorphism of EGFR Exon 19 and Use Thereof Public/Granted day:2012-11-08
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