Invention Grant
- Patent Title: Cyclic triazo sodium channel blockers
- Patent Title (中): 环状三唑钠通道阻滞剂
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Application No.: US13382720Application Date: 2010-07-08
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Publication No.: US08748599B2Publication Date: 2014-06-10
- Inventor: Michael Leach , Karl Franzmann , Dieter Riddall , Laurence Harbige
- Applicant: Michael Leach , Karl Franzmann , Dieter Riddall , Laurence Harbige
- Applicant Address: GB London
- Assignee: University Of Greenwich
- Current Assignee: University Of Greenwich
- Current Assignee Address: GB London
- Agency: Cesari and McKenna, LLP
- Priority: GB0911991.8 20090708; GB0911925.6 20090709; GB0912271.4 20090715
- International Application: PCT/GB2010/051126 WO 20100708
- International Announcement: WO2011/004195 WO 20110113
- Main IPC: C07D253/07
- IPC: C07D253/07 ; A61K31/53 ; A61P25/08 ; A61P25/28 ; A61P25/04
Abstract:
The present invention relates to triazine compounds having sodium channel blocking properties, and to use of the compounds for preparation of medicaments for treatment of associated disorders. The compounds are of formula (I): in which z is a single bond or an optionally substituted linking group, R1 is a halo-alkyl group; and A is an optionally substituted aromatic heterocyclic or carbocyclic ring system; or a salt thereof.
Public/Granted literature
- US20120135992A1 CYCLIC TRIAZO SODIUM CHANNEL BLOCKERS Public/Granted day:2012-05-31
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