Invention Grant
- Patent Title: Catalysis of diketopiperazine synthesis
- Patent Title (中): 二酮哌嗪合成的催化
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Application No.: US13422989Application Date: 2012-03-16
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Publication No.: US08748609B2Publication Date: 2014-06-10
- Inventor: John J. Stevenson , Destardi Moye-Sherman
- Applicant: John J. Stevenson , Destardi Moye-Sherman
- Applicant Address: US CA Valencia
- Assignee: MannKind Corporation
- Current Assignee: MannKind Corporation
- Current Assignee Address: US CA Valencia
- Agency: K&L Gates LLP
- Agent Louis C. Cullman; Hal Gibson
- Main IPC: C07D241/04
- IPC: C07D241/04
Abstract:
Provided is a method for the synthesis of N-protected bis-3,6-[4-aminobutyl]-2,5-diketopiperazine including the step of heating a solution of ε-amino protected lysine in the presence of a catalyst selected from the group consisting of sulfuric acid, phosphoric acid, and phosphorus pentoxide.
Public/Granted literature
- US20120178935A1 Catalysis of Diketopiperazine Synthesis Public/Granted day:2012-07-12
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