Invention Grant
- Patent Title: Di-fluoro containing compounds as cysteine protease inhibitors
- Patent Title (中): 二氟化合物作为半胱氨酸蛋白酶抑制剂
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Application No.: US13719024Application Date: 2012-12-18
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Publication No.: US08748649B2Publication Date: 2014-06-10
- Inventor: John O. Link , Craig J. Mossman , Jie Liu , Soon Hyung Woo
- Applicant: ViroBay, Inc.
- Applicant Address: US CA Menlo Park
- Assignee: Virobay, Inc.
- Current Assignee: Virobay, Inc.
- Current Assignee Address: US CA Menlo Park
- Agency: Kilpatrick Townsend & Stockton LLP
- Main IPC: C07C255/46
- IPC: C07C255/46 ; A61K31/26
Abstract:
The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S, and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
Public/Granted literature
- US20140018421A1 DI-FLUORO CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS Public/Granted day:2014-01-16
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