Invention Grant
US08758730B2 Compositions, use and method for the use of surface active proteins in topical drug delivery across keratin
有权
组合物，使用和使用表面活性蛋白在角蛋白局部药物递送中的应用
- Patent Title: Compositions, use and method for the use of surface active proteins in topical drug delivery across keratin
- Patent Title (中): 组合物，使用和使用表面活性蛋白在角蛋白局部药物递送中的应用
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Application No.: US13202112Application Date: 2010-02-19
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Publication No.: US08758730B2Publication Date: 2014-06-24
- Inventor: Andreas Buthe , Andreas Hafner , Franz Kaufmann , Babette Fiedler , Guido Meurer , Gordon Bradley
- Applicant: Andreas Buthe , Andreas Hafner , Franz Kaufmann , Babette Fiedler , Guido Meurer , Gordon Bradley
- Applicant Address: DE Zwingenberg
- Assignee: B.R.A.I.N. Biotechnology Research and Information Network AG
- Current Assignee: B.R.A.I.N. Biotechnology Research and Information Network AG
- Current Assignee Address: DE Zwingenberg
- Agency: Pillsbury Winthrop Shaw Pittman LLP
- Priority: EP09153770 20090226
- International Application: PCT/EP2010/052125 WO 20100219
- International Announcement: WO2010/097344 WO 20100902
- Main IPC: A61K47/42
- IPC: A61K47/42 ; A61Q3/00
Abstract:
The present invention provides the use of surface active proteins, especially class I and class II hydrophobins, in topically applied pharmaceutical formulations. The invention is particularly directed to topically applied pharmaceutical products for enhancing the penetration to achieve a transungual delivery of a prophylactically and/or therapeutically effective amount of an active ingredient (drug) to a patient (including animals and humans) into and/or through a nail, of the animal or human body, in order to treat one or more of a variety of diseases or disorders. Related embodiments of the invention are also disclosed.
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