Invention Grant
US08758762B2 Method for preparing recombinant antigen complex using rotavirus nanoparticle
有权
使用轮状病毒纳米粒子制备重组抗原复合物的方法
- Patent Title: Method for preparing recombinant antigen complex using rotavirus nanoparticle
- Patent Title (中): 使用轮状病毒纳米粒子制备重组抗原复合物的方法
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Application No.: US13095303Application Date: 2011-04-27
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Publication No.: US08758762B2Publication Date: 2014-06-24
- Inventor: Won Yong Kim , In Sik Chung , Jong-Bum Kim , Dong-Hwa Shon , Van Thai Than , Jang Won Yoon , Joo Hyoung Park , In-Hyuk Baek
- Applicant: Won Yong Kim , In Sik Chung , Jong-Bum Kim , Dong-Hwa Shon , Van Thai Than , Jang Won Yoon , Joo Hyoung Park , In-Hyuk Baek
- Applicant Address: KR Seoul
- Assignee: Chung-Ang University Industry-Academy Cooperation Foundation
- Current Assignee: Chung-Ang University Industry-Academy Cooperation Foundation
- Current Assignee Address: KR Seoul
- Agency: Clark & Elbing LLP
- Priority: KR10-2010-0041095 20100430
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/12 ; A61K39/29 ; G01N33/569
Abstract:
Disclosed are a construct for expressing a rotavirus antigen complex loaded with a heterologous virus epitope, a vaccine composition containing the rotavirus antigen complex, a virus-like particle of rotavirus containing the rotavirus antigen complex, and a vaccine composition containing the virus-like particle of rotavirus. According to the present disclosure, an antigen complex containing a rotavirus antigen as well as a heterologous virus epitope and a virus-like particle of rotavirus containing the antigen complex can be produced in large scale at low cost. Thus, the present disclosure may be applied for research and development of novel complex vaccines for rotavirus and heterologous virus.
Public/Granted literature
- US20110311573A1 Method for Preparing Recombinant Antigen Complex Using Rotavirus Nanoparticle Public/Granted day:2011-12-22
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